CMap Candidate Details

Structure:
CMap ID: C14974
Pert ID: BRD-K39484304
Compound Name: triptolide
Targets: --
MoA: --
SMILES: CC(C)[C@@]12O[C@H]2[C@@H]3O[C@]34[C@]5(O[C@H]5C[C@H]6C7=C(CC[C@@]64C)C(=O)OC7)[C@@H]1O
InchiKey: DFBIRQPKNDILPW-CIVMWXNOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24433 BRD-K39484304 A375 10 uM 6 h 0.0 0.0 0.0 0.41 1.45 2.22
24667 BRD-K39484304 A549 10 uM 6 h 0.0 0.0 0.0 0.24 0.84 0.13
24770 BRD-K39484304 HA1E 10 uM 6 h 0.0 0.0 0.0 0.37 1.32 1.61
24899 BRD-K39484304 HT29 10 uM 6 h 0.0 0.0 0.0 0.34 1.2 1.09
25018 BRD-K39484304 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25158 BRD-K39484304 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25507 BRD-K39484304 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
99923 BRD-K39484304 U2OS 15 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.59
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).