CMap Candidate Details

Structure:
CMap ID: C14979
Pert ID: BRD-K39503511
Compound Name: quiflapon
Targets: ALOX5AP
MoA: Leukotriene inhibitor
SMILES: CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(Cl)cc2)c2ccc(OCc3ccc4ccccc4n3)cc12
InchiKey: NZOONKHCNQFYCI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8939 BRD-K39503511 A375 80 uM 24 h 0.0 0.0 0.0 -0.37 -1.26 1.35
9099 BRD-K39503511 A549 80 uM 24 h 0.0 0.0 0.0 -0.36 -1.21 1.23
9419 BRD-K39503511 AGS 80 uM 6 h -0.27 -1.13 0.4 0.0 0.0 0.0
9726 BRD-K39503511 H1299 80 uM 6 h 0.25 1.06 0.18 -0.38 -1.27 1.39
10055 BRD-K39503511 HA1E 80 uM 6 h -0.28 -1.15 0.43 -0.45 -1.51 15.35
10357 BRD-K39503511 HCC515 80 uM 6 h -0.21 -0.88 0.03 0.0 0.0 0.0
10512 BRD-K39503511 HCT116 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10781 BRD-K39503511 HEPG2 80 uM 6 h 0.0 0.0 0.0 -0.45 -1.52 15.35
10973 BRD-K39503511 HT29 80 uM 24 h 0.29 1.23 0.5 -0.31 -1.04 0.65
11237 BRD-K39503511 MCF??7.00 80 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
11482 BRD-K39503511 NCIH2073 80 uM 6 h -0.28 -1.16 0.45 -0.26 -0.86 0.22
11760 BRD-K39503511 NCIH508 80 uM 6 h -0.21 -0.88 0.03 0.39 1.38 2.16
12046 BRD-K39503511 NCIH596 80 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.19
12311 BRD-K39503511 NOMO1 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12563 BRD-K39503511 PC3 80 uM 24 h 0.21 0.88 0.02 0.0 0.0 0.0
12787 BRD-K39503511 SW480 80 uM 6 h 0.0 0.0 0.0 -0.35 -1.19 1.16
13100 BRD-K39503511 THP1 80 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13268 BRD-K39503511 U937 80 uM 6 h 0.0 0.0 0.0 0.22 0.79 0.07
13618 BRD-K39503511 VCAP 80 uM 6 h 0.0 0.0 0.0 0.34 1.19 1.02
123594 BRD-K39503511 HEK293 0.125 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.92
123629 BRD-K39503511 HELA 10 uM 24 h 0.17 0.71 0.0 0.0 0.0 0.0
123709 BRD-K39503511 MCF10A 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.26 1.38
123775 BRD-K39503511 YAPC 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).