CMap Candidate Details

Structure:
CMap ID: C01502
Pert ID: BRD-A63043573
Compound Name: cabergoline
Targets: ADRA1A; ADRA2A; ADRA2B; ADRA2C; DRD1; DRD2; DRD3; DRD4; DRD5; HTR1A; HTR1B; HTR1D; HTR2A; HTR2B; HTR2C
MoA: Dopamine receptor agonist
SMILES: CCNC(=O)N(CCCN(C)C)C(=O)C1CC2C(Cc3c[nH]c4cccc2c34)N(CC=C)C1
InchiKey: KORNTPPJEAJQIU-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2814 BRD-A63043573 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3113 BRD-A63043573 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3586 BRD-A63043573 PC3 10 uM 6 h 0.0 0.0 0.0 -0.28 -0.94 0.38
3928 BRD-A63043573 VCAP 10 uM 6 h -0.23 -0.98 0.11 -0.31 -1.06 0.72
39053 BRD-A63043573 A375 10 uM 6 h -0.19 -0.8 0.0 -0.3 -1.0 0.52
39402 BRD-A63043573 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
39576 BRD-A63043573 ASC 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
39901 BRD-A63043573 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40185 BRD-A63043573 HT29 10 uM 6 h -0.3 -1.24 0.67 -0.28 -0.94 0.39
40571 BRD-A63043573 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40703 BRD-A63043573 NEU 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.0 0.54
41002 BRD-A63043573 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41325 BRD-A63043573 SKB 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.95
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).