CMap Candidate Details

Structure:
CMap ID: C01505
Pert ID: BRD-A63310107
Compound Name: miglitol
Targets: GAA; MGAM
MoA: Glucosidase inhibitor
SMILES: OCCN1C[C@@H](O)[C@@H](O)C(O)C1CO
InchiKey: IBAQFPQHRJAVAV-WMEPKMGJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
124995 BRD-A63310107 HA1E 10 uM 24 h 0.26 1.07 0.2 0.0 0.0 0.0
125052 BRD-A63310107 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125072 BRD-A63310107 MCF10A 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
125108 BRD-A63310107 MDAMB231 1.11 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
125157 BRD-A63310107 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132976 BRD-A63310107 A375 0.01 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
132995 BRD-A63310107 A549 2.22 uM 24 h 0.23 0.98 0.09 0.0 0.0 0.0
133043 BRD-A63310107 HEK293 0.03 uM 24 h 0.0 0.0 0.0 -0.41 -1.39 2.02
133088 BRD-A63310107 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.2 0.71 0.02
133150 BRD-A63310107 JURKAT 2.22 uM 24 h -0.17 -0.71 0.0 0.33 1.17 0.93
133223 BRD-A63310107 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.71
133288 BRD-A63310107 PC3 0.08 uM 24 h 0.0 0.0 0.0 -0.27 -0.9 0.29
133312 BRD-A63310107 YAPC 0.01 uM 24 h 0.21 0.88 0.01 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).