CMap Candidate Details

Structure:
CMap ID: C15085
Pert ID: BRD-K39823328
Compound Name: VU-0366037-2
Targets: GRM4
MoA: Glutamate receptor modulator
SMILES: Clc1ccccc1C(=O)Nc1ccc(NC(=O)c2ccccn2)cc1Cl
InchiKey: MTELUFOIWGSEFF-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
19034 BRD-K39823328 A375 10 uM 6 h -0.28 -1.18 0.5 -0.31 -1.04 0.66
19282 BRD-K39823328 A549 10 uM 24 h -0.2 -0.84 0.0 -0.22 -0.73 0.05
19680 BRD-K39823328 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20339 BRD-K39823328 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20658 BRD-K39823328 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
20903 BRD-K39823328 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.08
21417 BRD-K39823328 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
21575 BRD-K39823328 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).