CMap Candidate Details

Structure:
CMap ID: C15091
Pert ID: BRD-K39841531
Compound Name: TG-101209
Targets: JAK2; JAK3
MoA: JAK inhibitor
SMILES: CN1CCN(CC1)c1ccc(Nc2ncc(C)c(Nc3cccc(c3)S(=O)(=O)NC(C)(C)C)n2)cc1
InchiKey: JVDOKQYTTYUYDV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
96627 BRD-K39841531 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
96695 BRD-K39841531 PC3 3.33 uM 24 h 0.21 0.9 0.02 -0.3 -1.0 0.52
118724 BRD-K39841531 A549 10 uM 24 h 0.0 0.0 0.0 0.22 0.76 0.05
118761 BRD-K39841531 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118800 BRD-K39841531 HCC515 0.12 uM 24 h 0.0 0.0 0.0 0.2 0.69 0.01
118842 BRD-K39841531 HEPG2 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118885 BRD-K39841531 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118925 BRD-K39841531 MCF??7.00 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).