CMap Candidate Details

Structure:
CMap ID: C00151
Pert ID: BRD-A05874290
Compound Name: DL-TBOA
Targets: SLC1A1; SLC1A2; SLC1A3
MoA: Excitatory amino acid transporter inhibitor
SMILES: NC(C(OCc1ccccc1)C(=O)O)C(=O)O
InchiKey: BYOBCYXURWDEDS-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8857 BRD-A05874290 A375 150 uM 24 h -0.23 -0.96 0.09 -0.28 -0.93 0.35
9135 BRD-A05874290 A549 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9566 BRD-A05874290 H1299 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9906 BRD-A05874290 HA1E 150 uM 24 h 0.0 0.0 0.0 -0.2 -0.68 0.02
10285 BRD-A05874290 HCC515 150 uM 6 h -0.3 -1.24 0.65 0.0 0.0 0.0
10648 BRD-A05874290 HEPG2 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10892 BRD-A05874290 HT29 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11163 BRD-A05874290 MCF??7.00 150 uM 24 h -0.33 -1.37 1.08 -0.28 -0.94 0.37
11316 BRD-A05874290 NCIH2073 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12186 BRD-A05874290 NOMO1 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12474 BRD-A05874290 PC3 150 uM 24 h -0.25 -1.05 0.24 0.0 0.0 0.0
12643 BRD-A05874290 SW480 150 uM 6 h 0.29 1.2 0.43 0.0 0.0 0.0
12988 BRD-A05874290 THP1 150 uM 6 h 0.24 0.98 0.09 0.0 0.0 0.0
13125 BRD-A05874290 U937 150 uM 6 h 0.24 1.01 0.11 0.0 0.0 0.0
13414 BRD-A05874290 VCAP 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).