CMap Candidate Details

Structure:
CMap ID: C01513
Pert ID: BRD-A63546914
Compound Name: Ro-04-5595
Targets: GRIN2B
MoA: Glutamate receptor antagonist
SMILES: COc1cc2CCN(C)C(CCc3ccc(Cl)cc3)c2cc1O
InchiKey: DSTWURHEHMZWEI-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1701 BRD-A63546914 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.15 1.07
2045 BRD-A63546914 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2347 BRD-A63546914 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
2753 BRD-A63546914 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39055 BRD-A63546914 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39277 BRD-A63546914 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39578 BRD-A63546914 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39903 BRD-A63546914 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40187 BRD-A63546914 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40572 BRD-A63546914 MCF??7.00 10 uM 6 h -0.22 -0.91 0.06 0.25 0.89 0.2
40705 BRD-A63546914 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41326 BRD-A63546914 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100259 BRD-A63546914 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).