CMap Candidate Details
Structure:
| CMap ID: | C15134 |
| Pert ID: | BRD-K39983086 |
| Compound Name: | loteprednol |
| Targets: | NR3C1 |
| MoA: | Phospholipase inhibitor; Glucocorticoid receptor agonist |
| SMILES: | CCOC(=O)O[C@@]1(CC[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@H]3[C@@H](O)C[C@]12C)C(=O)OCCl |
| InchiKey: | DMKSVUSAATWOCU-HROMYWEYSA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 24435 | BRD-K39983086 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24669 | BRD-K39983086 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24772 | BRD-K39983086 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 24901 | BRD-K39983086 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.3 | 1.57 |
| 25096 | BRD-K39983086 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | -0.18 | -0.59 | 0.0 |
| 25160 | BRD-K39983086 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 25365 | BRD-K39983086 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |