CMap Candidate Details

Structure:
CMap ID: C15168
Pert ID: BRD-K40087974
Compound Name: BRD-K40087974
Targets: --
MoA: --
SMILES: COc1ccc(Sc2ccc(NC(=O)c3ccccc3Cl)cc2C#N)cc1
InchiKey: YZMLAJBOSVHFEW-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
13804 BRD-K40087974 A375 10 uM 24 h 0.27 1.11 0.26 -0.31 -1.04 0.68
14458 BRD-K40087974 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15054 BRD-K40087974 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
15924 BRD-K40087974 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
26353 BRD-K40087974 ASC 10 uM 24 h 0.25 1.03 0.13 -0.33 -1.12 0.93
28242 BRD-K40087974 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28875 BRD-K40087974 PHH 10 uM 24 h 0.0 0.0 0.0 0.24 0.84 0.13
29205 BRD-K40087974 SKB 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.96 0.43
115094 BRD-K40087974 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
118085 BRD-K40087974 A549 0.125 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.23
118172 BRD-K40087974 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
118221 BRD-K40087974 HEPG2 10 uM 24 h 0.26 1.08 0.22 -0.31 -1.06 0.72
118308 BRD-K40087974 MCF??7.00 10 uM 24 h 0.18 0.77 0.0 0.0 0.0 0.0
118348 BRD-K40087974 PC3 10 uM 24 h 0.24 0.99 0.1 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).