CMap Candidate Details

Structure:
CMap ID: C01517
Pert ID: BRD-A63646118
Compound Name: fumonisin-b1
Targets: CERS1
MoA: Sphingosine N acyltransferase inhibitor
SMILES: CCCC[C@@H](C)[C@@H](OC(=O)C[C@@H](CC(O)=O)C(O)=O)[C@H](CC(C)C[C@H](O)CCCC[C@@H](O)C[C@H](O)[C@H](C)N)OC(=O)C[C@@H](CC(O)=O)C(O)=O
InchiKey: UVBUBMSSQKOIBE-YPCSWJJOSA-N
Compound Aliases: FUMONISIN-B1

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8881 BRD-A63646118 A375 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9075 BRD-A63646118 A549 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9300 BRD-A63646118 AGS 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9605 BRD-A63646118 H1299 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9993 BRD-A63646118 HA1E 150 uM 24 h 0.0 0.0 0.0 0.22 0.79 0.08
10371 BRD-A63646118 HCC515 150 uM 6 h 0.0 0.0 0.0 0.27 0.97 0.34
10411 BRD-A63646118 HCT116 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10912 BRD-A63646118 HT29 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11252 BRD-A63646118 MCF??7.00 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11353 BRD-A63646118 NCIH2073 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11925 BRD-A63646118 NCIH596 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12570 BRD-A63646118 PC3 150 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12677 BRD-A63646118 SW480 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13543 BRD-A63646118 VCAP 150 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).