CMap Candidate Details

Structure:
CMap ID: C01524
Pert ID: BRD-A63836183
Compound Name: PD-123319
Targets: AGTR2
MoA: Angiotensin antagonist
SMILES: CN(C)c1ccc(Cn2cnc3CN(C(Cc32)C(=O)O)C(=O)C(c4ccccc4)c5ccccc5)cc1C
InchiKey: YSTVFDAKLDMYCR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1506 BRD-A63836183 HA1E 10 uM 24 h 0.21 0.87 0.01 -0.31 -1.03 0.65
1838 BRD-A63836183 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.44 -1.48 15.35
2252 BRD-A63836183 PC3 10 uM 24 h -0.29 -1.2 0.55 0.0 0.0 0.0
2733 BRD-A63836183 VCAP 10 uM 6 h 0.31 1.28 0.61 0.0 0.0 0.0
39057 BRD-A63836183 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39278 BRD-A63836183 A549 10 uM 24 h 0.0 0.0 0.0 -0.24 -0.8 0.11
39580 BRD-A63836183 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39905 BRD-A63836183 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.97 0.46
40189 BRD-A63836183 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40574 BRD-A63836183 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40706 BRD-A63836183 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41005 BRD-A63836183 NPC 10 uM 24 h 0.0 0.0 0.0 0.33 1.17 0.92
41327 BRD-A63836183 SKB 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.51
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).