CMap Candidate Details

Structure:
CMap ID: C01525
Pert ID: BRD-A63894585
Compound Name: clobetasol
Targets: NR3C1
MoA: Glucocorticoid receptor agonist
SMILES: CCC(=O)OC1([C@@H](C)C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@]4(C)[C@@]3(F)[C@@H](O)C[C@@]21C)C(=O)CCl
InchiKey: CBGUOGMQLZIXBE-DZLFUUCZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1703 BRD-A63894585 HA1E 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.96 0.44
1839 BRD-A63894585 HCC515 10 uM 24 h -0.17 -0.72 0.0 -0.35 -1.19 1.15
2349 BRD-A63894585 PC3 10 uM 6 h -0.23 -0.98 0.12 0.0 0.0 0.0
2510 BRD-A63894585 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41682 BRD-A63894585 A375 10 uM 6 h 0.0 0.0 0.0 -0.31 -1.03 0.64
41888 BRD-A63894585 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42226 BRD-A63894585 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42568 BRD-A63894585 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42873 BRD-A63894585 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43268 BRD-A63894585 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.12 0.95
44021 BRD-A63894585 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100262 BRD-A63894585 U2OS 4 uM 6 h 0.0 0.0 0.0 -0.31 -1.06 0.73
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).