CMap Candidate Details

Structure:
CMap ID: C01532
Pert ID: BRD-A64092382
Compound Name: mexiletine
Targets: SCN5A
MoA: Sodium channel blocker
SMILES: CC(N)COc1c(C)cccc1C
InchiKey: VLPIATFUUWWMKC-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5272 BRD-A64092382 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5851 BRD-A64092382 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6142 BRD-A64092382 PC3 10 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
6478 BRD-A64092382 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37091 BRD-A64092382 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37349 BRD-A64092382 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37530 BRD-A64092382 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38027 BRD-A64092382 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38159 BRD-A64092382 MCF??7.00 10 uM 24 h -0.19 -0.8 0.0 0.0 0.0 0.0
38377 BRD-A64092382 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
50304 BRD-A64092382 HCC515 10 uM 6 h 0.0 0.0 0.0 0.33 1.18 1.0
100263 BRD-A64092382 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).