CMap Candidate Details

Structure:
CMap ID: C15352
Pert ID: BRD-K40645748
Compound Name: mefloquine
Targets: --
MoA: --
SMILES: O[C@H]([C@H]1CCCCN1)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F
InchiKey: XEEQGYMUWCZPDN-DOMZBBRYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49837 BRD-K40645748 A375 10 uM 6 h -0.24 -1.01 0.16 0.0 0.0 0.0
50005 BRD-K40645748 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50182 BRD-K40645748 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50359 BRD-K40645748 HCC515 10 uM 6 h 0.0 0.0 0.0 0.36 1.26 1.29
50530 BRD-K40645748 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50749 BRD-K40645748 MCF??7.00 10 uM 6 h 0.2 0.83 0.0 0.29 1.01 0.45
50927 BRD-K40645748 PC3 10 uM 6 h 0.0 0.0 0.0 0.19 0.67 0.01
51145 BRD-K40645748 VCAP 10 uM 6 h -0.26 -1.09 0.33 0.4 1.41 2.19
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).