CMap Candidate Details

Structure:
CMap ID: C01540
Pert ID: BRD-A64297288
Compound Name: amlodipine
Targets: CACNA1C; CACNA1D; CACNA1S; CACNA2D1
MoA: Calcium channel blocker
SMILES: CCOC(=O)C1=C(NC(=C(C1C2=CC=CC=C2Cl)C(=O)OC)C)COCCN
InchiKey: HTIQEAQVCYTUBX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
24392 BRD-A64297288 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24539 BRD-A64297288 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.14 0.85
24731 BRD-A64297288 HA1E 10 uM 6 h -0.23 -0.96 0.1 0.0 0.0 0.0
24851 BRD-A64297288 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24992 BRD-A64297288 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
25221 BRD-A64297288 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
25301 BRD-A64297288 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).