CMap Candidate Details

Structure:
CMap ID: C15415
Pert ID: BRD-K40887525
Compound Name: ritanserin
Targets: HTR2A; HTR2B; HTR2C
MoA: Serotonin receptor antagonist
SMILES: Cc1nc2sccn2c(=O)c1CCN1CCC(CC1)=C(c1ccc(F)cc1)c1ccc(F)cc1
InchiKey: JUQLTPCYUFPYKE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5328 BRD-K40887525 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.1 0.88
5626 BRD-K40887525 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
5913 BRD-K40887525 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.21 -0.72 0.04
6278 BRD-K40887525 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6342 BRD-K40887525 VCAP 10 uM 24 h -0.16 -0.66 0.0 0.26 0.92 0.25
37154 BRD-K40887525 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37384 BRD-K40887525 A549 10 uM 6 h 0.22 0.92 0.04 0.0 0.0 0.0
37653 BRD-K40887525 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38081 BRD-K40887525 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38203 BRD-K40887525 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38478 BRD-K40887525 NPC 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.87 0.22
38718 BRD-K40887525 PHH 10 uM 24 h 0.2 0.82 0.0 -0.25 -0.85 0.19
38952 BRD-K40887525 SKB 10 uM 24 h -0.25 -1.03 0.2 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).