CMap Candidate Details

Structure:
CMap ID: C15416
Pert ID: BRD-K40892394
Compound Name: AR-C133057XX
Targets: NOS2
MoA: Nitric oxide synthase inhibitor
SMILES: COc1ccnc(NC2CCN(CC2)C(=O)c2ccc(cc2)C#N)c1
InchiKey: SZUVGMCKKLJAFX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8940 BRD-K40892394 A375 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9202 BRD-K40892394 A549 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9727 BRD-K40892394 H1299 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10056 BRD-K40892394 HA1E 12 uM 6 h 0.0 0.0 0.0 -0.24 -0.8 0.12
10169 BRD-K40892394 HCC515 12 uM 24 h 0.0 0.0 0.0 -0.35 -1.19 1.15
10783 BRD-K40892394 HEPG2 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11080 BRD-K40892394 HT29 12 uM 6 h -0.19 -0.78 0.0 -0.3 -1.0 0.55
11175 BRD-K40892394 MCF??7.00 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
11763 BRD-K40892394 NCIH508 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12048 BRD-K40892394 NCIH596 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12314 BRD-K40892394 NOMO1 12 uM 6 h -0.21 -0.89 0.03 0.0 0.0 0.0
12491 BRD-K40892394 PC3 12 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
12789 BRD-K40892394 SW480 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13269 BRD-K40892394 U937 12 uM 6 h 0.21 0.87 0.01 0.36 1.28 1.37
13620 BRD-K40892394 VCAP 12 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).