CMap Candidate Details

Structure:
CMap ID: C15428
Pert ID: BRD-K40919711
Compound Name: BAPTA-AM
Targets: KCNA3; KCNA5; KCNH2
MoA: Potassium channel blocker
SMILES: CC(=O)OCOC(=O)CN(CC(=O)OCOC(=O)C)c1ccccc1OCCOc2ccccc2N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C
InchiKey: YJIYWYAMZFVECX-UHFFFAOYSA-N
Compound Aliases: bapta-am

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1584 BRD-K40919711 HA1E 10 uM 24 h 0.32 1.32 0.79 0.33 1.15 0.9
2104 BRD-K40919711 HCC515 10 uM 6 h -0.29 -1.19 0.53 -0.31 -1.04 0.65
2395 BRD-K40919711 PC3 10 uM 6 h 0.0 0.0 0.0 0.26 0.91 0.23
2653 BRD-K40919711 VCAP 10 uM 6 h 0.26 1.09 0.22 0.0 0.0 0.0
41768 BRD-K40919711 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42094 BRD-K40919711 A549 10 uM 6 h -0.18 -0.77 0.0 0.0 0.0 0.0
42360 BRD-K40919711 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42686 BRD-K40919711 HEPG2 10 uM 6 h -0.2 -0.85 0.01 0.0 0.0 0.0
42988 BRD-K40919711 HT29 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.29
43188 BRD-K40919711 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
43550 BRD-K40919711 NPC 10 uM 24 h 0.2 0.84 0.0 -0.31 -1.04 0.68
43848 BRD-K40919711 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).