CMap Candidate Details

Structure:
CMap ID: C01543
Pert ID: BRD-A64479082
Compound Name: quinidine
Targets: SCN5A
MoA: Sodium channel blocker
SMILES: COc1ccc2nccc(C(O)C3CC4CCN3CC4C=C)c2c1
InchiKey: LOUPRKONTZGTKE-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49773 BRD-A64479082 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
49954 BRD-A64479082 A549 10 uM 6 h 0.18 0.74 0.0 -0.24 -0.81 0.12
50116 BRD-A64479082 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50467 BRD-A64479082 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50636 BRD-A64479082 MCF??7.00 10 uM 24 h -0.23 -0.96 0.1 0.23 0.8 0.08
50891 BRD-A64479082 PC3 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.1 0.87
51103 BRD-A64479082 VCAP 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.88 0.26
98734 BRD-A64479082 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98978 BRD-A64479082 NEU 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).