CMap Candidate Details

Structure:
CMap ID: C15504
Pert ID: BRD-K41160163
Compound Name: fenobam
Targets: GRM5
MoA: Glutamate receptor antagonist
SMILES: CN1CC(=O)N=C1NC(=O)Nc1cccc(Cl)c1
InchiKey: DWPQODZAOSWNHB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4221 BRD-K41160163 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
4572 BRD-K41160163 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5083 BRD-K41160163 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39452 BRD-K41160163 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39698 BRD-K41160163 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40006 BRD-K41160163 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
98145 BRD-K41160163 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98380 BRD-K41160163 NEU 10 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
123526 BRD-K41160163 A375 10 uM 24 h 0.0 0.0 0.0 0.3 1.04 0.56
123600 BRD-K41160163 HEK293 0.04 uM 24 h 0.22 0.9 0.02 -0.34 -1.13 0.98
123667 BRD-K41160163 HT29 1.11 uM 24 h -0.2 -0.81 0.0 -0.25 -0.86 0.21
123715 BRD-K41160163 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 -0.23 -0.77 0.09
123752 BRD-K41160163 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132050 BRD-K41160163 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132095 BRD-K41160163 MCF??7.00 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132153 BRD-K41160163 YAPC 2.22 uM 24 h 0.0 0.0 0.0 -0.29 -0.97 0.45
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).