CMap Candidate Details

Structure:
CMap ID: C15524
Pert ID: BRD-K41213548
Compound Name: KW-2478
Targets: --
MoA: --
SMILES: CCc1c(O)cc(O)c(C(=O)c2ccc(OCCN3CCOCC3)c(OC)c2)c1CC(=O)N(CCOC)CCOC
InchiKey: VFUXSYAXEKYYMB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1244 BRD-K41213548 A549 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1286 BRD-K41213548 MCF??7.00 1.11 uM 48 h 0.0 0.0 0.0 0.0 0.0 0.0
1384 BRD-K41213548 U2OS 10 uM 6 h 0.0 0.0 0.0 0.3 1.06 0.59
123314 BRD-K41213548 HELA 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
123343 BRD-K41213548 HT29 0.37 uM 24 h -0.23 -0.94 0.08 0.0 0.0 0.0
123367 BRD-K41213548 MCF10A 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123424 BRD-K41213548 PC3 3.33 uM 24 h 0.21 0.87 0.01 0.0 0.0 0.0
123461 BRD-K41213548 THP1 3.33 uM 24 h 0.0 0.0 0.0 -0.24 -0.82 0.15
131528 BRD-K41213548 A375 2.22 uM 24 h 0.29 1.2 0.42 0.27 0.97 0.35
131590 BRD-K41213548 HA1E 2.22 uM 24 h -0.24 -0.99 0.14 -0.26 -0.88 0.25
131631 BRD-K41213548 HEK293 2.22 uM 24 h -0.28 -1.17 0.48 -0.26 -0.89 0.27
131729 BRD-K41213548 HUVEC 2.22 uM 24 h -0.26 -1.1 0.34 0.0 0.0 0.0
131783 BRD-K41213548 JURKAT 2.22 uM 24 h -0.21 -0.89 0.04 0.0 0.0 0.0
131895 BRD-K41213548 MDAMB231 2.22 uM 24 h 0.18 0.73 0.0 0.0 0.0 0.0
131957 BRD-K41213548 YAPC 2.22 uM 24 h -0.2 -0.83 0.0 0.32 1.15 0.88
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).