CMap Candidate Details
Structure:
CMap ID: | C15560 |
Pert ID: | BRD-K41337261 |
Compound Name: | ZM-306416 |
Targets: | FLT1; KDR |
MoA: | Src inhibitor; VEGFR inhibitor; Abl kinase inhibitor |
SMILES: | COc1cc2ncnc(Nc3ccc(Cl)cc3F)c2cc1OC |
InchiKey: | YHUIUSRCUKUUQA-UHFFFAOYSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
2881 | BRD-K41337261 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
3201 | BRD-K41337261 | HCC515 | 10 uM | 24 h | 0.22 | 0.91 | 0.04 | 0.4 | 1.41 | 2.19 |
3504 | BRD-K41337261 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
3797 | BRD-K41337261 | VCAP | 10 uM | 24 h | 0.21 | 0.89 | 0.02 | 0.0 | 0.0 | 0.0 |
39137 | BRD-K41337261 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
39327 | BRD-K41337261 | A549 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.33 | 1.15 | 0.9 |
39699 | BRD-K41337261 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
40007 | BRD-K41337261 | HEPG2 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
40278 | BRD-K41337261 | HT29 | 10 uM | 6 h | 0.18 | 0.77 | 0.0 | 0.31 | 1.09 | 0.67 |
40473 | BRD-K41337261 | MCF??7.00 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | -0.38 | -1.28 | 1.45 |
40815 | BRD-K41337261 | NEU | 10 uM | 24 h | -0.27 | -1.1 | 0.36 | 0.0 | 0.0 | 0.0 |
41119 | BRD-K41337261 | NPC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
41454 | BRD-K41337261 | SKB | 10 uM | 24 h | -0.2 | -0.84 | 0.01 | -0.21 | -0.71 | 0.04 |
99515 | BRD-K41337261 | U2OS | 10 uM | 6 h | 0.24 | 0.99 | 0.1 | 0.0 | 0.0 | 0.0 |