CMap Candidate Details

Structure:
CMap ID: C15583
Pert ID: BRD-K41410256
Compound Name: balsalazide
Targets: PTGS1; PTGS2
MoA: Cyclooxygenase inhibitor
SMILES: OC(=O)CCNC(=O)c1ccc(cc1)N=Nc1ccc(O)c(c1)C(O)=O
InchiKey: IPOKCKJONYRRHP-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
22286 BRD-K41410256 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
22768 BRD-K41410256 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23057 BRD-K41410256 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
24156 BRD-K41410256 VCAP 10 uM 24 h 0.0 0.0 0.0 -0.27 -0.91 0.29
95457 BRD-K41410256 U2OS 0.12 uM 6 h 0.27 1.11 0.25 0.0 0.0 0.0
123315 BRD-K41410256 HELA 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123344 BRD-K41410256 HT29 0.37 uM 24 h 0.25 1.05 0.16 -0.29 -0.97 0.46
123462 BRD-K41410256 THP1 1.11 uM 24 h -0.32 -1.34 0.98 0.0 0.0 0.0
123496 BRD-K41410256 YAPC 0.125 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131529 BRD-K41410256 A375 0.01 uM 24 h 0.0 0.0 0.0 -0.27 -0.92 0.32
131591 BRD-K41410256 HA1E 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131632 BRD-K41410256 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131730 BRD-K41410256 HUVEC 0.01 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.37
131784 BRD-K41410256 JURKAT 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131827 BRD-K41410256 MCF10A 0.03 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.64
131861 BRD-K41410256 MCF??7.00 0.74 uM 24 h -0.29 -1.22 0.61 0.0 0.0 0.0
131896 BRD-K41410256 MDAMB231 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131918 BRD-K41410256 PC3 2.22 uM 24 h 0.0 0.0 0.0 -0.43 -1.45 15.35
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).