CMap Candidate Details

Structure:
CMap ID: C01560
Pert ID: BRD-A65013509
Compound Name: oxybutynin
Targets: CHRM1; CHRM2; CHRM3
MoA: Acetylcholine receptor antagonist
SMILES: CCN(CC)CC#CCOC(=O)C(O)(C1CCCCC1)c1ccccc1
InchiKey: XIQVNETUBQGFHX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
50305 BRD-A65013509 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50986 BRD-A65013509 VCAP 10 uM 24 h 0.0 0.0 0.0 0.34 1.2 1.13
100269 BRD-A65013509 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
124580 BRD-A65013509 A375 10 uM 24 h 0.0 0.0 0.0 0.23 0.82 0.1
124598 BRD-A65013509 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124618 BRD-A65013509 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124661 BRD-A65013509 HELA 10 uM 24 h 0.27 1.12 0.26 0.0 0.0 0.0
124800 BRD-A65013509 MDAMB231 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124840 BRD-A65013509 PC3 0.04 uM 24 h 0.0 0.0 0.0 0.31 1.11 0.72
124882 BRD-A65013509 THP1 10 uM 24 h 0.0 0.0 0.0 -0.35 -1.17 1.14
124917 BRD-A65013509 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132757 BRD-A65013509 HEK293 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132811 BRD-A65013509 HT29 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132836 BRD-A65013509 JURKAT 2.22 uM 24 h 0.19 0.79 0.0 -0.25 -0.86 0.21
132872 BRD-A65013509 MCF10A 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132900 BRD-A65013509 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).