CMap Candidate Details

Structure:
CMap ID: C15600
Pert ID: BRD-K41438959
Compound Name: perampanel
Targets: GRIA1
MoA: Glutamate receptor antagonist
SMILES: O=c1c(cc(cn1-c1ccccc1)-c1ccccn1)-c1ccccc1C#N
InchiKey: PRMWGUBFXWROHD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
121554 BRD-K41438959 A375 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121592 BRD-K41438959 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121632 BRD-K41438959 HELA 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121655 BRD-K41438959 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
121673 BRD-K41438959 MCF??7.00 10 uM 24 h 0.18 0.74 0.0 -0.32 -1.09 0.84
121699 BRD-K41438959 YAPC 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
129683 BRD-K41438959 PC3 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).