CMap Candidate Details
Structure:
| CMap ID: | C15603 |
| Pert ID: | BRD-K41445866 |
| Compound Name: | alfaxalone |
| Targets: | GABBR1 |
| MoA: | GABA receptor agonist; Chloride channel agonist |
| SMILES: | CC(=O)[C@H]1CC[C@H]2[C@@H]3CC[C@H]4C[C@H](O)CC[C@]4(C)[C@H]3C(=O)C[C@]12C |
| InchiKey: | DUHUCHOQIDJXAT-OLVMNOGESA-N |
| Compound Aliases: | -- |
| Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
|---|---|---|---|---|---|---|---|---|---|---|
| 6748 | BRD-K41445866 | A375 | 10 uM | 24 h | -0.21 | -0.86 | 0.02 | -0.27 | -0.92 | 0.33 |
| 7152 | BRD-K41445866 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7443 | BRD-K41445866 | HA1E | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 7997 | BRD-K41445866 | HT29 | 10 uM | 6 h | -0.24 | -1.0 | 0.15 | 0.0 | 0.0 | 0.0 |
| 8170 | BRD-K41445866 | MCF??7.00 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 8505 | BRD-K41445866 | PC3 | 10 uM | 6 h | -0.33 | -1.37 | 1.08 | -0.33 | -1.12 | 0.93 |
| 8673 | BRD-K41445866 | VCAP | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
| 99517 | BRD-K41445866 | U2OS | 6.66 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |