CMap Candidate Details
Structure:
CMap ID: | C15632 |
Pert ID: | BRD-K41567364 |
Compound Name: | SB-334867 |
Targets: | HCRTR1 |
MoA: | Orexin receptor antagonist |
SMILES: | Cc1nc2ccc(NC(=O)Nc3ccnc4cccnc34)cc2o1 |
InchiKey: | AKMNUCBQGHFICM-UHFFFAOYSA-N |
Compound Aliases: | -- |
Score ID | Pert ID | Cell Line | Pert Dose | Pert Time | Raw Score (GSE126848) | Normalized Score (GSE126848) | fdr_q_nlog10 (GSE126848) | Raw Score (GSE135251) | Normalized Score (GSE135251) | fdr_q_nlog10 (GSE135251) |
---|---|---|---|---|---|---|---|---|---|---|
4113 | BRD-K41567364 | HA1E | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
4573 | BRD-K41567364 | HCC515 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
4688 | BRD-K41567364 | PC3 | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
5084 | BRD-K41567364 | VCAP | 10 uM | 6 h | 0.23 | 0.96 | 0.08 | -0.29 | -0.99 | 0.51 |
44397 | BRD-K41567364 | A375 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
44705 | BRD-K41567364 | A549 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.32 | 1.15 | 0.88 |
44961 | BRD-K41567364 | ASC | 10 uM | 24 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
45256 | BRD-K41567364 | HEPG2 | 10 uM | 6 h | -0.23 | -0.98 | 0.12 | 0.0 | 0.0 | 0.0 |
45526 | BRD-K41567364 | HT29 | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 | 0.0 |
45696 | BRD-K41567364 | MCF??7.00 | 10 uM | 24 h | 0.23 | 0.98 | 0.09 | 0.0 | 0.0 | 0.0 |
46076 | BRD-K41567364 | NPC | 10 uM | 24 h | -0.2 | -0.84 | 0.01 | 0.0 | 0.0 | 0.0 |
46393 | BRD-K41567364 | PHH | 10 uM | 24 h | -0.24 | -1.0 | 0.15 | 0.0 | 0.0 | 0.0 |
46714 | BRD-K41567364 | SKB | 10 uM | 24 h | 0.24 | 0.99 | 0.1 | 0.39 | 1.37 | 2.02 |
99519 | BRD-K41567364 | U2OS | 10 uM | 6 h | 0.0 | 0.0 | 0.0 | 0.21 | 0.76 | 0.05 |