CMap Candidate Details

Structure:
CMap ID: C01568
Pert ID: BRD-A65280694
Compound Name: molindone
Targets: DRD2; HTR2A
MoA: Dopamine receptor antagonist
SMILES: CCc1c(C)[nH]c2CCC(CN3CCOCC3)C(=O)c12
InchiKey: KLPWJLBORRMFGK-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
49955 BRD-A65280694 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
50306 BRD-A65280694 HCC515 10 uM 6 h 0.27 1.14 0.32 0.0 0.0 0.0
50987 BRD-A65280694 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100273 BRD-A65280694 U2OS 6.66 uM 6 h -0.17 -0.71 0.0 0.0 0.0 0.0
124589 BRD-A65280694 A375 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
124817 BRD-A65280694 MDAMB231 0.04 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
124860 BRD-A65280694 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132732 BRD-A65280694 HA1E 0.08 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
132774 BRD-A65280694 HEK293 2.22 uM 24 h 0.0 0.0 0.0 -0.19 -0.64 0.01
132799 BRD-A65280694 HELA 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132818 BRD-A65280694 HT29 0.01 uM 24 h 0.22 0.92 0.04 0.2 0.72 0.02
132848 BRD-A65280694 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132888 BRD-A65280694 MCF10A 0.25 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132913 BRD-A65280694 MCF??7.00 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
132937 BRD-A65280694 THP1 0.74 uM 24 h 0.0 0.0 0.0 -0.32 -1.09 0.82
132970 BRD-A65280694 YAPC 0.01 uM 24 h 0.25 1.03 0.14 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).