CMap Candidate Details

Structure:
CMap ID: C15680
Pert ID: BRD-K41713976
Compound Name: E-4031
Targets: KCNH2
MoA: Potassium channel blocker
SMILES: Cc1cccc(CCN2CCC(CC2)C(=O)c2ccc(NS(C)(=O)=O)cc2)n1
InchiKey: SRUISGSHWFJION-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5205 BRD-K41713976 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5329 BRD-K41713976 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.36 -1.2 1.22
5627 BRD-K41713976 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
23058 BRD-K41713976 HEPG2 10 uM 6 h -0.28 -1.18 0.51 -0.28 -0.96 0.42
23357 BRD-K41713976 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
23855 BRD-K41713976 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
24157 BRD-K41713976 VCAP 10 uM 24 h 0.0 0.0 0.0 0.28 0.99 0.4
41933 BRD-K41713976 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
42361 BRD-K41713976 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43319 BRD-K41713976 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.32 -1.09 0.82
43551 BRD-K41713976 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
43849 BRD-K41713976 PHH 10 uM 24 h 0.31 1.27 0.58 0.0 0.0 0.0
44115 BRD-K41713976 SKB 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.05 0.7
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).