CMap Candidate Details

Structure:
CMap ID: C15709
Pert ID: BRD-K41783120
Compound Name: STA-5326
Targets: IL12A
MoA: Interleukin synthesis inhibitor
SMILES: Cc1cccc(C=NNc2cc(nc(OCCc3ccccn3)n2)N2CCOCC2)c1
InchiKey: HSKAZIJJKRAJAV-KOEQRZSOSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
123262 BRD-K41783120 A549 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123316 BRD-K41783120 HELA 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123346 BRD-K41783120 HT29 0.37 uM 24 h -0.14 -0.6 0.0 0.0 0.0 0.0
123368 BRD-K41783120 MCF10A 3.33 uM 24 h 0.0 0.0 0.0 0.27 0.95 0.32
123399 BRD-K41783120 MDAMB231 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123426 BRD-K41783120 PC3 10 uM 24 h 0.0 0.0 0.0 0.38 1.34 1.72
123464 BRD-K41783120 THP1 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131531 BRD-K41783120 A375 2.22 uM 24 h 0.16 0.68 0.0 0.3 1.08 0.64
131593 BRD-K41783120 HA1E 0.08 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131634 BRD-K41783120 HEK293 2.22 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131732 BRD-K41783120 HUVEC 2.22 uM 24 h 0.0 0.0 0.0 -0.28 -0.94 0.36
131786 BRD-K41783120 JURKAT 2.22 uM 24 h 0.21 0.87 0.01 0.41 1.45 2.22
131863 BRD-K41783120 MCF??7.00 0.74 uM 24 h -0.19 -0.78 0.0 0.34 1.22 1.15
131958 BRD-K41783120 YAPC 2.22 uM 24 h 0.0 0.0 0.0 0.36 1.29 1.42
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).