CMap Candidate Details

Structure:
CMap ID: C15727
Pert ID: BRD-K41859756
Compound Name: NVP-AUY922
Targets: HSP90AA1; HSP90AB1
MoA: HSP inhibitor
SMILES: CCNC(=O)c1noc(c1-c1ccc(CN2CCOCC2)cc1)-c1cc(C(C)C)c(O)cc1O
InchiKey: NDAZATDQFDPQBD-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1178 BRD-K41859756 PC3 0.08 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
1404 BRD-K41859756 U2OS 10 uM 6 h 0.0 0.0 0.0 0.32 1.14 0.87
9037 BRD-K41859756 A375 10 uM 6 h -0.27 -1.13 0.41 0.0 0.0 0.0
9423 BRD-K41859756 AGS 10 uM 6 h 0.0 0.0 0.0 0.39 1.39 2.17
9728 BRD-K41859756 H1299 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10057 BRD-K41859756 HA1E 10 uM 6 h 0.0 0.0 0.0 0.27 0.96 0.33
10303 BRD-K41859756 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10515 BRD-K41859756 HCT116 10 uM 6 h 0.0 0.0 0.0 -0.34 -1.14 1.03
10786 BRD-K41859756 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11083 BRD-K41859756 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11279 BRD-K41859756 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11487 BRD-K41859756 NCIH2073 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.77 0.08
11766 BRD-K41859756 NCIH508 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.99 0.51
12051 BRD-K41859756 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12317 BRD-K41859756 NOMO1 10 uM 6 h -0.32 -1.32 0.83 0.21 0.76 0.05
12791 BRD-K41859756 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13014 BRD-K41859756 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13272 BRD-K41859756 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13474 BRD-K41859756 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91804 BRD-K41859756 HS578T 10 uM 6 h -0.2 -0.84 0.01 0.0 0.0 0.0
91841 BRD-K41859756 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91913 BRD-K41859756 MDAMB231 2.22 uM 6 h 0.0 0.0 0.0 0.3 1.07 0.63
91960 BRD-K41859756 SKBR3 0.08 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
96141 BRD-K41859756 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).