CMap Candidate Details

Structure:
CMap ID: C01573
Pert ID: BRD-A65449987
Compound Name: flunisolide
Targets: NR3C1
MoA: Cytochrome P450 inhibitor
SMILES: CC1(C)O[C@@H]2CC3C4C[C@H](F)C5=CC(=O)C=CC5(C)C4C(O)CC3(C)[C@@]2(O1)C(=O)CO
InchiKey: XSFJVAJPIHIPKU-CCRGDLLISA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
4023 BRD-A65449987 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4528 BRD-A65449987 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.35 -1.17 1.14
4623 BRD-A65449987 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
4862 BRD-A65449987 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37092 BRD-A65449987 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37246 BRD-A65449987 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37531 BRD-A65449987 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
37839 BRD-A65449987 HEPG2 10 uM 6 h -0.26 -1.1 0.34 -0.3 -1.0 0.55
38028 BRD-A65449987 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38160 BRD-A65449987 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38378 BRD-A65449987 NPC 10 uM 24 h 0.24 0.99 0.09 -0.34 -1.15 1.08
38878 BRD-A65449987 SKB 10 uM 24 h 0.26 1.07 0.2 -0.33 -1.11 0.92
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).