CMap Candidate Details

Structure:
CMap ID: C15746
Pert ID: BRD-K41895714
Compound Name: AS-605240
Targets: PIK3CG
MoA: PI3K inhibitor
SMILES: O=C1NC(=O)C(S1)=C/c1ccc2nccnc2c1
InchiKey: SQWZFLMPDUSYGV-UXBLZVDNSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
9203 BRD-K41895714 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9424 BRD-K41895714 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9729 BRD-K41895714 H1299 10 uM 6 h 0.0 0.0 0.0 0.31 1.09 0.67
9882 BRD-K41895714 HA1E 10 uM 24 h -0.21 -0.86 0.02 -0.33 -1.11 0.88
10258 BRD-K41895714 HCC515 10 uM 6 h 0.0 0.0 0.0 0.37 1.31 1.59
10516 BRD-K41895714 HCT116 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
10787 BRD-K41895714 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11060 BRD-K41895714 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11488 BRD-K41895714 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11767 BRD-K41895714 NCIH508 10 uM 6 h -0.35 -1.45 1.43 0.32 1.12 0.77
12052 BRD-K41895714 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12318 BRD-K41895714 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.23 0.8 0.08
12792 BRD-K41895714 SW480 10 uM 6 h 0.24 1.01 0.12 0.0 0.0 0.0
12941 BRD-K41895714 THP1 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13273 BRD-K41895714 U937 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13475 BRD-K41895714 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
91507 BRD-K41895714 BT20 10 uM 24 h 0.22 0.94 0.05 0.34 1.2 1.1
91748 BRD-K41895714 SKBR3 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92569 BRD-K41895714 HME1 10 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92594 BRD-K41895714 HS578T 3.33 uM 24 h 0.17 0.72 0.0 0.3 1.07 0.62
92686 BRD-K41895714 LNCAP 3.33 uM 24 h -0.19 -0.78 0.0 0.0 0.0 0.0
92717 BRD-K41895714 MCF10A 0.04 uM 24 h 0.0 0.0 0.0 0.3 1.07 0.61
92780 BRD-K41895714 MDAMB231 10 uM 24 h -0.19 -0.81 0.0 -0.35 -1.16 1.11
95448 BRD-K41895714 U2OS 0.12 uM 6 h 0.0 0.0 0.0 -0.22 -0.73 0.05
97265 BRD-K41895714 HAP1 3.33 uM 24 h 0.2 0.82 0.0 0.0 0.0 0.0
124282 BRD-K41895714 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124329 BRD-K41895714 HEK293 3.33 uM 24 h 0.0 0.0 0.0 -0.26 -0.88 0.25
124368 BRD-K41895714 HELA 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.06 0.72
124436 BRD-K41895714 JURKAT 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124472 BRD-K41895714 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.28 1.45
124528 BRD-K41895714 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
124561 BRD-K41895714 YAPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).