CMap Candidate Details

Structure:
CMap ID: C01577
Pert ID: BRD-A65597028
Compound Name: RX-821002
Targets: ADRA2A; ADRA2B; ADRA2C
MoA: Adrenergic receptor antagonist
SMILES: COC1(COc2ccccc2O1)C1=NCCN1
InchiKey: HQGWKNGAKBPTBX-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6673 BRD-A65597028 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7103 BRD-A65597028 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7404 BRD-A65597028 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7575 BRD-A65597028 HCC515 10 uM 6 h 0.0 0.0 0.0 -0.33 -1.11 0.9
7795 BRD-A65597028 HT29 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
8057 BRD-A65597028 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
8322 BRD-A65597028 PC3 10 uM 24 h 0.0 0.0 0.0 0.32 1.13 0.82
8608 BRD-A65597028 VCAP 10 uM 24 h -0.22 -0.91 0.06 0.0 0.0 0.0
100275 BRD-A65597028 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).