CMap Candidate Details

Structure:
CMap ID: C15772
Pert ID: BRD-K41996876
Compound Name: tyrphostin-1
Targets: --
MoA: --
SMILES: COc1ccc(C=C(C#N)C#N)cc1
InchiKey: UOHFCPXBKJPCAD-UHFFFAOYSA-N
Compound Aliases: TYRPHOSTIN-1

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
8942 BRD-K41996876 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
9425 BRD-K41996876 AGS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
9730 BRD-K41996876 H1299 10 uM 6 h 0.0 0.0 0.0 0.28 1.0 0.43
10246 BRD-K41996876 HCC515 10 uM 6 h -0.24 -1.0 0.14 0.0 0.0 0.0
10517 BRD-K41996876 HCT116 10 uM 6 h 0.0 0.0 0.0 0.28 0.99 0.4
10788 BRD-K41996876 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.28 0.99 0.4
11051 BRD-K41996876 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
11489 BRD-K41996876 NCIH2073 10 uM 6 h 0.0 0.0 0.0 0.42 1.48 2.25
12053 BRD-K41996876 NCIH596 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
12319 BRD-K41996876 NOMO1 10 uM 6 h 0.0 0.0 0.0 0.26 0.92 0.25
12793 BRD-K41996876 SW480 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
13274 BRD-K41996876 U937 10 uM 6 h -0.28 -1.17 0.48 0.0 0.0 0.0
13621 BRD-K41996876 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
44962 BRD-K41996876 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46077 BRD-K41996876 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
46394 BRD-K41996876 PHH 10 uM 24 h 0.21 0.87 0.01 -0.26 -0.88 0.24
46715 BRD-K41996876 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128242 BRD-K41996876 MCF10A 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128271 BRD-K41996876 MCF??7.00 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
128321 BRD-K41996876 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 -0.29 -0.99 0.5
128341 BRD-K41996876 PC3 0.04 uM 24 h -0.27 -1.12 0.39 -0.24 -0.82 0.14
135784 BRD-K41996876 A549 0.01 uM 24 h 0.0 0.0 0.0 -0.32 -1.07 0.78
135826 BRD-K41996876 HA1E 0.03 uM 24 h 0.0 0.0 0.0 0.25 0.89 0.21
135865 BRD-K41996876 HEK293 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
135916 BRD-K41996876 HELA 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
136006 BRD-K41996876 JURKAT 0.74 uM 24 h 0.0 0.0 0.0 -0.33 -1.11 0.9
136099 BRD-K41996876 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.31 1.1 0.7
136152 BRD-K41996876 YAPC 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).