CMap Candidate Details

Structure:
CMap ID: C01580
Pert ID: BRD-A65671304
Compound Name: candesartan-cilextil
Targets: AGTR1
MoA: Angiotensin receptor antagonist
SMILES: CCOc1nc2cccc(C(=O)OC(C)OC(=O)OC3CCCCC3)c2n1Cc1ccc(cc1)-c1ccccc1-c1nnn[nH]1
InchiKey: GHOSNRCGJFBJIB-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5408 BRD-A65671304 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5539 BRD-A65671304 HCC515 10 uM 24 h 0.0 0.0 0.0 0.3 1.05 0.56
6074 BRD-A65671304 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6144 BRD-A65671304 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6480 BRD-A65671304 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37093 BRD-A65671304 A375 10 uM 6 h -0.24 -0.99 0.13 0.0 0.0 0.0
37350 BRD-A65671304 A549 10 uM 6 h -0.22 -0.91 0.05 0.0 0.0 0.0
37532 BRD-A65671304 ASC 10 uM 24 h 0.0 0.0 0.0 -0.38 -1.26 1.39
37840 BRD-A65671304 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.28 0.98 0.36
38029 BRD-A65671304 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38379 BRD-A65671304 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100277 BRD-A65671304 U2OS 10 uM 6 h 0.16 0.68 0.0 -0.3 -1.01 0.56
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).