CMap Candidate Details

Structure:
CMap ID: C01582
Pert ID: BRD-A65739223
Compound Name: ramipril
Targets: ACE
MoA: Angiotensin converting enzyme inhibitor
SMILES: CCOC(=O)[C@H](CCc1ccccc1)N[C@@H](C)C(=O)N2C(C[C@@H]3CCC[C@@H]32)C(=O)O
InchiKey: HDACQVRGBOVJII-QJUJLUFUSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6675 BRD-A65739223 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7104 BRD-A65739223 A549 10 uM 6 h 0.0 0.0 0.0 -0.36 -1.2 1.21
7406 BRD-A65739223 HA1E 10 uM 6 h -0.22 -0.9 0.04 0.0 0.0 0.0
7577 BRD-A65739223 HCC515 10 uM 6 h -0.3 -1.24 0.65 -0.28 -0.93 0.35
8198 BRD-A65739223 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 -0.27 -0.91 0.3
8323 BRD-A65739223 PC3 10 uM 24 h -0.23 -0.96 0.1 -0.35 -1.17 1.14
8609 BRD-A65739223 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
100278 BRD-A65739223 U2OS 4 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).