CMap Candidate Details

Structure:
CMap ID: C01583
Pert ID: BRD-A65767837
Compound Name: hydrocortisone-acetate
Targets: NR3C1
MoA: Corticosteroid agonist; Glucocorticoid receptor agonist
SMILES: CC(=O)OCC(=O)[C@@]1(O)CCC2C3CCC4=CC(=O)CC[C@]4(C)C3[C@@H](O)C[C@]12C
InchiKey: ALEXXDVDDISNDU-KPYZGQEZSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6676 BRD-A65767837 A375 10 uM 24 h 0.19 0.78 0.0 0.29 1.01 0.45
6947 BRD-A65767837 A549 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
7255 BRD-A65767837 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.33 -1.09 0.85
7578 BRD-A65767837 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7964 BRD-A65767837 HT29 10 uM 6 h 0.0 0.0 0.0 -0.24 -0.79 0.11
8127 BRD-A65767837 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.2 0.7 0.01
8465 BRD-A65767837 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8610 BRD-A65767837 VCAP 10 uM 24 h -0.21 -0.89 0.03 -0.34 -1.14 1.03
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).