CMap Candidate Details

Structure:
CMap ID: C15831
Pert ID: BRD-K42221274
Compound Name: NNC-711
Targets: SLC6A1
MoA: GAT inhibitor
SMILES: OC(=O)C1=CCCN(CCON=C(c2ccccc2)c2ccccc2)C1
InchiKey: NGNALWDRPKNJGR-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2882 BRD-K42221274 HA1E 10 uM 24 h 0.0 0.0 0.0 -0.3 -1.02 0.62
3202 BRD-K42221274 HCC515 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3623 BRD-K42221274 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3798 BRD-K42221274 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39138 BRD-K42221274 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39328 BRD-K42221274 A549 10 uM 24 h -0.27 -1.13 0.4 0.0 0.0 0.0
39700 BRD-K42221274 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40008 BRD-K42221274 HEPG2 10 uM 6 h 0.23 0.96 0.08 0.0 0.0 0.0
40279 BRD-K42221274 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40474 BRD-K42221274 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
40816 BRD-K42221274 NEU 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41120 BRD-K42221274 NPC 10 uM 24 h 0.2 0.84 0.0 0.25 0.88 0.19
41455 BRD-K42221274 SKB 10 uM 24 h -0.21 -0.88 0.03 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).