CMap Candidate Details

Structure:
CMap ID: C15965
Pert ID: BRD-K42693031
Compound Name: glimepiride
Targets: KCNJ11; ABCC8
MoA: Insulin secretagogue
SMILES: CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)NC3CCC(C)CC3)C1=O
InchiKey: WIGIZIANZCJQQY-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
3025 BRD-K42693031 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3203 BRD-K42693031 HCC515 10 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
3624 BRD-K42693031 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3800 BRD-K42693031 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41770 BRD-K42693031 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
41935 BRD-K42693031 A549 10 uM 24 h -0.28 -1.17 0.48 0.0 0.0 0.0
42363 BRD-K42693031 ASC 10 uM 24 h 0.0 0.0 0.0 0.36 1.28 1.37
42990 BRD-K42693031 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43190 BRD-K42693031 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.34 -1.16 1.1
43851 BRD-K42693031 PHH 10 uM 24 h -0.25 -1.04 0.21 -0.23 -0.78 0.1
44117 BRD-K42693031 SKB 10 uM 24 h 0.0 0.0 0.0 0.28 0.98 0.38
99532 BRD-K42693031 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).