CMap Candidate Details

Structure:
CMap ID: C00160
Pert ID: BRD-A06304526
Compound Name: alvespimycin
Targets: HSP90AA1
MoA: HSP inhibitor
SMILES: COC1CC(C)CC2=C(NCCN(C)C)C(=O)C=C(NC(=O)C(C)=CC=CC(OC)C(OC(N)=O)C(C)=CC(C)C1O)C2=O
InchiKey: KUFRQPKVAWMTJO-UBRRALEVSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1130 BRD-A06304526 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
1140 BRD-A06304526 PC3 0.37 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
88142 BRD-A06304526 VCAP 20 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99262 BRD-A06304526 U2OS 20 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).