CMap Candidate Details

Structure:
CMap ID: C01601
Pert ID: BRD-A66563878
Compound Name: medetomidine
Targets: ADRA2A; ADRA2B; ADRA2C
MoA: Adrenergic receptor agonist
SMILES: CC(c1cnc[nH]1)c2cccc(C)c2C
InchiKey: CUHVIMMYOGQXCV-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
6678 BRD-A66563878 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
6949 BRD-A66563878 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
7408 BRD-A66563878 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7581 BRD-A66563878 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
7797 BRD-A66563878 HT29 10 uM 24 h -0.18 -0.74 0.0 0.33 1.15 0.89
8274 BRD-A66563878 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
8325 BRD-A66563878 PC3 10 uM 24 h 0.0 0.0 0.0 0.35 1.23 1.21
8772 BRD-A66563878 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
100282 BRD-A66563878 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).