CMap Candidate Details

Structure:
CMap ID: C16031
Pert ID: BRD-K42918627
Compound Name: GSK-2126458
Targets: --
MoA: --
SMILES: COc1nccc(-c2ccc3nccc(-c4ccnnc4)c3c2)c1NS(=O)(=O)c1ccc(F)cc1F
InchiKey: NPPBBAURRJGWEH-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
91877 BRD-K42918627 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
91914 BRD-K42918627 MDAMB231 10 uM 6 h -0.21 -0.86 0.02 -0.31 -1.03 0.65
92421 BRD-K42918627 A375 1.11 uM 24 h 0.0 0.0 0.0 -0.22 -0.74 0.05
92443 BRD-K42918627 A549 0.12 uM 24 h -0.17 -0.73 0.0 -0.35 -1.18 1.15
92480 BRD-K42918627 BT20 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92512 BRD-K42918627 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92545 BRD-K42918627 HME1 3.33 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.62
92611 BRD-K42918627 HS578T 3.33 uM 3 h 0.0 0.0 0.0 0.0 0.0 0.0
92641 BRD-K42918627 HT29 0.37 uM 24 h 0.0 0.0 0.0 0.24 0.85 0.14
92702 BRD-K42918627 LNCAP 10 uM 3 h 0.23 0.95 0.06 0.22 0.78 0.07
92750 BRD-K42918627 MCF10A 3.33 uM 3 h -0.31 -1.29 0.79 0.0 0.0 0.0
92816 BRD-K42918627 PC3 3.33 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
92854 BRD-K42918627 SKBR3 1.11 uM 3 h 0.0 0.0 0.0 -0.23 -0.76 0.07
119680 BRD-K42918627 HEPG2 1.11 uM 24 h 0.0 0.0 0.0 0.23 0.81 0.09
119767 BRD-K42918627 JURKAT 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).