CMap Candidate Details

Structure:
CMap ID: C01608
Pert ID: BRD-A66927094
Compound Name: nemonapride
Targets: DRD2; DRD3
MoA: Dopamine receptor antagonist
SMILES: CNc1cc(OC)c(cc1Cl)C(=O)NC2CCN(Cc3ccccc3)C2C
InchiKey: KRVOJOCLBAAKSJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
1508 BRD-A66927094 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2049 BRD-A66927094 HCC515 10 uM 6 h -0.25 -1.05 0.23 -0.26 -0.87 0.24
2272 BRD-A66927094 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
2755 BRD-A66927094 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39060 BRD-A66927094 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
39280 BRD-A66927094 A549 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39584 BRD-A66927094 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
39907 BRD-A66927094 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40191 BRD-A66927094 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
40432 BRD-A66927094 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
41331 BRD-A66927094 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98310 BRD-A66927094 NEU 10 uM 24 h -0.24 -0.98 0.12 -0.25 -0.85 0.2
98602 BRD-A66927094 NPC 10 uM 24 h 0.0 0.0 0.0 0.25 0.88 0.19
100284 BRD-A66927094 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).