CMap Candidate Details

Structure:
CMap ID: C16087
Pert ID: BRD-K43068349
Compound Name: AMG-9810
Targets: TRPV1
MoA: TRPV antagonist
SMILES: CC(C)(C)c1ccc(C=CC(=O)Nc2ccc3OCCOc3c2)cc1
InchiKey: GZTFUVZVLYUPRG-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5332 BRD-K43068349 HA1E 10 uM 24 h 0.0 0.0 0.0 0.26 0.91 0.24
5633 BRD-K43068349 HCC515 10 uM 24 h -0.23 -0.96 0.09 -0.3 -1.01 0.58
6280 BRD-K43068349 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6549 BRD-K43068349 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37160 BRD-K43068349 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37387 BRD-K43068349 A549 10 uM 6 h 0.0 0.0 0.0 -0.23 -0.78 0.09
37661 BRD-K43068349 ASC 10 uM 24 h 0.0 0.0 0.0 0.3 1.08 0.65
37905 BRD-K43068349 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.25 -0.85 0.2
38085 BRD-K43068349 HT29 10 uM 6 h 0.0 0.0 0.0 0.31 1.11 0.72
38204 BRD-K43068349 MCF??7.00 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.03 0.63
38486 BRD-K43068349 NPC 10 uM 24 h 0.0 0.0 0.0 0.44 1.54 2.31
38725 BRD-K43068349 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38957 BRD-K43068349 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
99535 BRD-K43068349 U2OS 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).