CMap Candidate Details

Structure:
CMap ID: C16109
Pert ID: BRD-K43164539
Compound Name: cholic-acid
Targets: CES1; FECH; PLA2G1B
MoA: Bile acid
SMILES: C[C@H](CCC(O)=O)[C@H]1CC[C@H]2[C@@H]3[C@H](O)C[C@@H]4C[C@H](O)CC[C@]4(C)[C@H]3C[C@H](O)[C@]12C
InchiKey: BHQCQFFYRZLCQQ-OELDTZBJSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
34107 BRD-K43164539 ASC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
34624 BRD-K43164539 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
34890 BRD-K43164539 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.26 -0.89 0.26
36268 BRD-K43164539 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
36566 BRD-K43164539 SKB 10 uM 24 h -0.28 -1.16 0.48 -0.32 -1.06 0.75
36824 BRD-K43164539 VCAP 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
98811 BRD-K43164539 NPC 10 uM 6 h 0.0 0.0 0.0 -0.38 -1.28 1.45
99043 BRD-K43164539 NEU 10 uM 6 h -0.22 -0.92 0.06 -0.27 -0.92 0.34
123247 BRD-K43164539 A375 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123294 BRD-K43164539 HEK293 1.11 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123321 BRD-K43164539 HELA 10 uM 24 h 0.0 0.0 0.0 -0.31 -1.04 0.68
123354 BRD-K43164539 HT29 0.04 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123405 BRD-K43164539 MDAMB231 0.37 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
123504 BRD-K43164539 YAPC 0.37 uM 24 h -0.26 -1.08 0.31 0.0 0.0 0.0
131559 BRD-K43164539 A549 0.01 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131599 BRD-K43164539 HA1E 2.22 uM 24 h 0.23 0.97 0.08 0.0 0.0 0.0
131741 BRD-K43164539 HUVEC 0.03 uM 24 h -0.23 -0.96 0.09 0.0 0.0 0.0
131795 BRD-K43164539 JURKAT 0.74 uM 24 h 0.25 1.06 0.18 0.0 0.0 0.0
131831 BRD-K43164539 MCF10A 0.08 uM 24 h 0.0 0.0 0.0 0.28 1.0 0.42
131869 BRD-K43164539 MCF??7.00 0.25 uM 24 h 0.26 1.1 0.25 -0.28 -0.94 0.37
131920 BRD-K43164539 PC3 0.03 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
131938 BRD-K43164539 THP1 2.22 uM 24 h 0.0 0.0 0.0 0.29 1.03 0.5
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).