CMap Candidate Details

Structure:
CMap ID: C16142
Pert ID: BRD-K43245338
Compound Name: MDL-28170
Targets: CTSB; CAPN1
MoA: Calpain inhibitor
SMILES: CC(C)[C@H](NC(=O)OCc1ccccc1)C(=O)N[C@@H](Cc2ccccc2)C=O
InchiKey: NGBKFLTYGSREKK-PMACEKPBSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
2883 BRD-K43245338 HA1E 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
3368 BRD-K43245338 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
3801 BRD-K43245338 VCAP 10 uM 24 h -0.22 -0.92 0.06 0.0 0.0 0.0
42095 BRD-K43245338 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42364 BRD-K43245338 ASC 10 uM 24 h -0.24 -0.99 0.14 0.0 0.0 0.0
42688 BRD-K43245338 HEPG2 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
42991 BRD-K43245338 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43320 BRD-K43245338 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
43553 BRD-K43245338 NPC 10 uM 24 h 0.0 0.0 0.0 0.33 1.16 0.91
43852 BRD-K43245338 PHH 10 uM 24 h 0.24 0.99 0.1 -0.24 -0.81 0.13
44118 BRD-K43245338 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96473 BRD-K43245338 A375 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
96539 BRD-K43245338 PC3 1.11 uM 24 h 0.2 0.84 0.0 -0.3 -0.99 0.51
99537 BRD-K43245338 U2OS 12.5 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).