CMap Candidate Details

Structure:
CMap ID: C01616
Pert ID: BRD-A67438293
Compound Name: treprostinil
Targets: PTGIR
MoA: Prostacyclin analog
SMILES: CCCCC[C@H](O)CC[C@H]1[C@H](O)CC2Cc3c(C)cccc3CC12
InchiKey: OLMBOBKKGZYZNU-OYQUQHOHSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
25578 BRD-A67438293 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26044 BRD-A67438293 A549 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26212 BRD-A67438293 ASC 10 uM 24 h -0.35 -1.47 1.43 0.0 0.0 0.0
26556 BRD-A67438293 HA1E 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
26873 BRD-A67438293 HCC515 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27176 BRD-A67438293 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
27475 BRD-A67438293 MCF??7.00 10 uM 24 h 0.17 0.71 0.0 0.36 1.28 1.37
28112 BRD-A67438293 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28425 BRD-A67438293 PC3 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
28750 BRD-A67438293 PHH 10 uM 24 h 0.0 0.0 0.0 -0.29 -0.98 0.48
29063 BRD-A67438293 SKB 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
29589 BRD-A67438293 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).