CMap Candidate Details

Structure:
CMap ID: C16160
Pert ID: BRD-K43290182
Compound Name: Ro-04-6790
Targets: HTR6
MoA: Serotonin receptor antagonist
SMILES: CNc1cc(NS(=O)(=O)c2ccc(N)cc2)nc(NC)n1
InchiKey: JELFWSXQTXRMAJ-UHFFFAOYSA-N
Compound Aliases: --

Score ID Pert ID Cell Line Pert Dose Pert Time Raw Score (GSE126848) Normalized Score (GSE126848) fdr_q_nlog10 (GSE126848) Raw Score (GSE135251) Normalized Score (GSE135251) fdr_q_nlog10 (GSE135251)
5206 BRD-K43290182 A375 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
5333 BRD-K43290182 HA1E 10 uM 24 h -0.26 -1.09 0.33 0.0 0.0 0.0
5634 BRD-K43290182 HCC515 10 uM 24 h 0.0 0.0 0.0 -0.28 -0.95 0.42
5916 BRD-K43290182 HEPG2 10 uM 6 h 0.0 0.0 0.0 -0.29 -0.98 0.47
6099 BRD-K43290182 MCF??7.00 10 uM 6 h 0.0 0.0 0.0 0.29 1.02 0.49
6281 BRD-K43290182 PC3 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
6550 BRD-K43290182 VCAP 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
37289 BRD-K43290182 A549 10 uM 24 h 0.0 0.0 0.0 0.32 1.15 0.88
37662 BRD-K43290182 ASC 10 uM 24 h 0.22 0.9 0.02 0.27 0.94 0.29
38086 BRD-K43290182 HT29 10 uM 6 h 0.0 0.0 0.0 0.0 0.0 0.0
38487 BRD-K43290182 NPC 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
38726 BRD-K43290182 PHH 10 uM 24 h 0.0 0.0 0.0 0.0 0.0 0.0
The GSE89632 and GSE126848 datasets are hepatic gene expression profiles of nonalcoholic fatty liver disease (NAFLD).